Endocrine Abstracts

Apelin is a new adipokine associated with obesity. Data about the relationship of apelin to the metabolic syndrome (MS) are still scarce. Late-onset hypogonadism (LOH) is common in men with MS, but we did not find data about the levels of apelin in men with LOH.The aim of this study was to determine the levels of apelin in men with MS with or without LOH.Patients and methods: Ninety nine men were included in the study. Of them 65 h...

The identification of type 2 diabetes patients at particularly high risk for cardiovascular events might be facilitated by the use of specific risk calculators or by measurements of serum biomarkers.Objectives: To correlate the levels of cardiovascular biomarkers – assymetric dymethylarginine (ADMA), endothelin 1 (ET-1), N-terminal brain natriuretic pro-peptide (NT-proBNP) and placental growth factor (PIGF-1), with calculated cardiovascular risks us...

Aims: To explore the correlations of BMI, waist circumference (WC), waist–to–height ratio (WHtR), waist–to–hip ratio (WHR) and body composition with levels of assymetric dymethylarginine (ADMA), endothelin 1(ET–1), N–terminal brain natriuretic pro–peptide (NT–proBNP), uric acid and calculated cardiovascular risks.Methods: 102 women and 67 men with type 2 diabetes on oral antidiabetic drugs participated. Ser...

Background: Chronic low-grade inflammation is a major factor in the pathogenesis of type 2 diabetes. One way for promoting inflammatory cytokines secretion is through activation of toll-like receptors (TLR). Their overexpression on monocytes has been demonstrated in insulin resistance and type 2 diabetes. Soluble forms of toll-like receptors (sTLR) are considered a regulatory mechanisms of their activation. Their role has been described in modulation of bacteria-induced infect...

Primary hyperparathyroidism (PHPT) is being more and more frequently diagnosed.Objectiveto describe the clinical presentation and the main laboratory and imaging findings in a group of patients with PHPT diagnosed during the last 10 years. Materials and Methods: This was a retrospective cross-sectional study with data review from the last 10 years. Secondary causes for elevated PTH were excluded. The symptoms and signs of hypercalc...